Contact allergy to cinnamon case report Assignment

Contact allergy to cinnamon case report - Assignment Example nickel, palladium, gold and mercury used in dental amalgam may also cause contact stomatitis. Allergic contact stomatitis is classified as type IV hypersensitivity reaction and prone to people who have previously been sensitized to the allergen. Its reaction falls under â€Å"delayed hypersensitivity reaction† as it several hours or even a day for the antigen reaction to become evident. The allergic process occurs in two phases namely the induction phase and the effector phase. In the induction phase, the allergens which have infiltrated and bound themselves to epithelial protein thus forming complexes are phagocytised by macrophages, specialized cells. The cells then move to regional ganglia stimulating production of the memory T lymphocytes. These lymphocytes are responsible for keeping memory of the antigen so as to trigger a more rapid immune response in the event of subsequent occurrences of the antigen. The effector phase is characterised with the activation and production of T lymphocytes (CD4 cells) by the cytotoxic T lymphocytes (CD8 cells) produces in the fi rst phase. The cytotoxic T lymphocytes bind to the epithelial cells causing the death of cells that present the complexes. There are two basic reasons as to why this condition is not common despite high rates of exposure to the allergens: first, saliva ensures constant cleaning of the mucosa thus minimizing contact time with the allergen; and, second, the high degree of vascularisation of the mucosa increases the rate of antigen absorption, reducing further prolonged exposure to these substances. Contact stomatitis manifest in a number of symptoms which include tissular edema, erythema, cracking, ulcerative areas, hyperkeratosis, desquamation, and vesicles. They manifest in the area that is exposed to the causal agent and may be with or without pain. Its appearance is determined